Last reviewed: October 2026 · Cleared Peptides research team
Research use only. Mitoprime Blend: NAD+, MOTS-c, and 5-Amino-1MQ is supplied for laboratory research. It is not a drug, food, cosmetic, or dietary supplement. It is not FDA-approved. It is not for human or veterinary administration. This page does not give a dose or a method of administration. A study cited on this page describes that study’s own test article. It does not make this lot an approved medicine. To check a fact, open the PubMed or DOI link, confirm the authors and year, and match the paper’s compound name, CAS number, or sequence to the specification table. The full method is on the research desk page. Identity and purity for a lot are only what that lot’s certificate of analysis reports. An HPLC percentage is not a sterility result and not an endotoxin result unless the certificate prints those tests.
Mitoprime blend on this page means a research combination of three materials that already have their own guides: NAD+, MOTS-c, and 5-Amino-1MQ. No milligram ratio is printed. Cleared Peptides does not have a lot of this blend, so a ratio would be an invention.
A separate commercial ingredient uses the MitoPrime name for fermented L-ergothioneine. That is a different material. This page is not that ingredient and does not use its claims.
| Catalog name on this page | Mitoprime blend |
|---|---|
| Components | NAD+; MOTS-c; 5-Amino-1MQ |
| Ratio | Not stated. There is no Cleared Peptides lot. |
| Not this page | Fermented L-ergothioneine sold under a similar brand name. |
| Class | Three-component research blend. Only MOTS-c is a peptide. |
Where the component chemistry lives
NAD+ is the nicotinamide adenine dinucleotide cofactor, CAS 53-84-9 on its own guide. MOTS-c is the mitochondrial open reading frame peptide on its own guide. 5-Amino-1MQ is the small-molecule NNMT inhibitor on its own guide. Read those pages for identifiers. This page only records that the blend name refers to the three together.
Analytical testing notes for Mitoprime blend
Mitoprime blend is identified in this guide. An identity test compares a measurement with those values. A mass spectrum is the usual measurement for a peptide. FTIR, when a certificate uses it, is a supporting infrared fingerprint and is less specific for closely related sequences.
This page compares more than one component. A single purity percentage is ambiguous unless the certificate says whether each component was resolved, identified, and quantified. Identity and content should be traceable to each named material. A chromatogram with several intentional peaks is expected; those peaks are not automatically impurities.
HPLC purity for this material is an area-percent result at the wavelength and gradient the laboratory states, commonly ultraviolet detection near 214 nm on a reversed-phase column. The instrument is a gradient pump, injector, column oven, and UV or diode-array detector. That percentage is not the number of milligrams in the vial. Water, acetate, trifluoroacetate, and other UV-silent material can dominate the gross weight while the purity figure stays high. Net peptide content, from an assay or amino-acid analysis, is the separate result to read when the certificate reports it.
A sterility test and an endotoxin test are not included in a chemical purity result. The compendial sterility test is a culture method (USP <71>): membrane filtration or direct inoculation into fluid thioglycollate medium and soybean-casein digest medium, incubated for 14 days. A PCR sterility screen uses a thermal cycler to detect microbial DNA and is a different method. The endotoxin test (USP <85> LAL, or USP <86> recombinant Factor C) reports endotoxin units with an incubating reader or a cartridge reader. Use a result only when that method is printed on the lot certificate. One published example in this catalog states that the report does not cover microbial contamination or endotoxins. The full description of equipment, standards, and how US laboratory accreditation works is in peptide analytical testing. Lot records are on the COA page.
Frequently Asked Questions
What is in the blend?
NAD+, MOTS-c, and 5-Amino-1MQ. No amounts are stated.
Is this the ergothioneine ingredient with a similar name?
No. That is a different material.
Is this for human use?
No. Laboratory reference only.
Selected References
Registry records and peer-reviewed literature listed as scientific background. Citation does not imply endorsement, a benefit, or any use.
- Component identity is on the NAD+, MOTS-c, and 5-Amino-1MQ guides linked above. No paper is cited for the three-component blend as one test article, because this page does not claim that a published study of the blend exists.
Research Use Only Notice
This guide is provided for educational and laboratory reference purposes. It summarizes published structural and biochemical literature. It does not describe, recommend, or imply any use in humans or animals. These materials are not drugs, foods, cosmetics, or dietary supplements on this page, are not offered here as a treatment, and no dosing or administration instructions are provided. Cleared Peptides does not currently list a lot for every compound on this page.
