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Ipamorelin

$46.00

Ipamorelin is a research material associated with growth-factor pathway research. Intended for laboratory research and analytical use only; not for human or veterinary use.

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Molecular Structure Explorer

Ipamorelin

Structure of the compound on this page.

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Molecular structure of Ipamorelin

Data from PubChem (NCBI) or a reviewed manual entry, shown only after review. 3D models are computed conformers, not experimental structures. Browsing does not change the product, option or cart. For laboratory research use only.

Product Details

Ipamorelin – Research Grade

Ipamorelin from Cleared Peptides is a research-grade compound supplied for laboratory and analytical investigation. Every lot is third-party tested, and the batch Certificate of Analysis is published before sale. Specifications, CAS number and molecular formula are listed below.

Research use only. Ipamorelin is supplied for laboratory research. It is not a drug, food, cosmetic, or dietary supplement. It is not FDA-approved. It is not for human or veterinary administration. This page does not give a dose or a method of administration. A study cited on this page describes that study’s own test article. It does not make this lot an approved medicine. To check a fact, open the PubMed or DOI link, confirm the authors and year, and match the paper’s compound name, CAS number, or sequence to the specification table. The full method is on the research desk page. Identity and purity for a lot are only what that lot’s certificate of analysis reports. An HPLC percentage is not a sterility result and not an endotoxin result unless the certificate prints those tests.

Ipamorelin Specifications

CompoundIpamorelin
SynonymsNNC 26-0161
CAS Number170851-70-4
PubChem CID9831659
Molecular FormulaC38H49N9O5
Molecular Weight711.9 g/mol
Sequence / StructureAib-His-D-2Nal-D-Phe-Lys-NH2
FormLyophilized (freeze-dried) powder
Purity≥99% by HPLC (verified per batch – see COA)
StorageStore at −20 °C, sealed, dry and protected from light. Allow vial to reach room temperature before opening.

Ipamorelin in Published Research

Ipamorelin is a synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) characterized as a selective agonist of the growth-hormone secretagogue receptor (GHSR-1a, the ghrelin receptor).

It is a reference ligand in GHSR receptor-binding and signaling studies, and is frequently compared with GHRH analogs such as tesamorelin.

This summary describes published laboratory research only and makes no claim about effects in humans or animals.

Purity Testing & Certificate of Analysis

Each lot of Ipamorelin is analyzed by an independent laboratory, with identity and purity (or composition, for multi-component preparations) reported on a lot-specific Certificate of Analysis. View current results on our COA page.

Storage & Laboratory Handling

Store at −20 °C, sealed, dry and protected from light. Allow vial to reach room temperature before opening. Minimize freeze–thaw cycles and handle according to your institution’s chemical-hygiene procedures.

Frequently Asked Questions

Is Ipamorelin third-party tested?

Yes. Every lot of Ipamorelin is tested by an independent laboratory for identity and purity, and the batch Certificate of Analysis is published on our COA page.

Can I see the Ipamorelin Certificate of Analysis before ordering?

Yes. Lot-specific COAs are posted on our COA page so you can review analytical data before purchase.

What does Research Use Only (RUO) mean?

RUO products are supplied solely for laboratory and analytical research. They are not medicines, are not for human or veterinary use, and no dosing or administration information is provided.

How should Ipamorelin be stored?

Store at −20 °C, sealed, dry and protected from light. Allow vial to reach room temperature before opening.

Research Guides

Learn more: Ipamorelin research guide

Written by the Cleared Peptides Research Desk, the editorial desk of Cleared Wellness Group LLC. This is not a personal profile of a physician or a scientist, and it is not a fictional author. The checking method is public on the research desk page. Last reviewed October 2026.

Ipamorelin research note: a pentapeptide secretagogue, not a GHRH analogue

Research use only. This ipamorelin material is for laboratory research, code NNC 26-0161, CAS 170851-70-4. It is not for human or veterinary administration. The cell-assay numbers below are the paper’s numbers. They are not a dose.

What Raun and colleagues measured

Raun, Hansen, Johansen, and colleagues (European Journal of Endocrinology, 1998) describe ipamorelin as the pentapeptide Aib-His-D-2-Nal-D-Phe-Lys-NH2, selected from a series that removed the central Ala-Trp dipeptide of GHRP-1. In primary rat pituitary cells they report growth-hormone release with EC50 1.3 ± 0.4 nmol/L and Emax 85 ± 5 percent, close to GHRP-6 in that assay (2.2 ± 0.3 nmol/L, Emax 100 percent). Antagonist experiments in the paper place the activity on a GHRP-like receptor, which is the ghrelin-receptor pathway, not the GHRH receptor. The title’s word “selective” is their claim from a hormone panel in the models they ran. A reader should look at that panel in the paper rather than treat the adjective as a new measurement. They also report growth-hormone release in pentobarbital-anaesthetized rats. That is an animal pharmacology result. PubMed 9849822, DOI 10.1530/eje.0.1390552.

The catalog table matches the sequence, formula C38H49N9O5, mass about 711.9 g/mol. Aib and D-2-naphthylalanine are not proteinogenic. An identity method that assumes twenty standard amino acids will mis-assign the mass. Stereochemistry at the D residues is part of the specification.

Why tesamorelin is the wrong comparison compound to merge with it

Tesamorelin is a 44-residue analogue of growth hormone-releasing hormone. Falutz’s trial studied that analogue as a drug. Ipamorelin is five residues and, in Raun’s antagonist experiments, uses the GHRP receptor. Both conversations are about growth hormone. The receptors are different, the masses are different (about 711.9 versus about 5135.9), and the papers are not interchangeable. There is also no basis on this site for mixing ipamorelin with MOTS-c or tesamorelin and citing either paper for the mixture.

How to verify this note

  1. Open Raun 1998 and confirm the sequence and the 1.3 nmol/L EC50 in rat pituitary cells. Leave that number in the assay.
  2. Match CAS 170851-70-4. A GHRP-6 mass is not an ipamorelin mass, even though the paper uses GHRP-6 as the comparator.
  3. Lot identity stays on the certificate.

Selected References

Peer-reviewed literature on Ipamorelin, listed as scientific background for laboratory researchers. Citation does not imply endorsement by the authors or any use other than in-vitro research.

  1. Raun K, et al. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. 1998;139(5):552-61. PubMed 9849822 · DOI
  2. Ankersen M, et al. A new series of highly potent growth hormone-releasing peptides derived from ipamorelin. J Med Chem. 1998;41(19):3699-704. PubMed 9733495 · DOI

Related Research Compounds

Research Use Only

For laboratory research use only. This product is not a drug, food, cosmetic or dietary supplement, is not FDA-approved, and is not intended for human or veterinary use or for the diagnosis, treatment, cure, mitigation or prevention of any disease. No dosing, administration or therapeutic information is provided. Sold only to qualified researchers; the purchaser is responsible for safe handling and compliance with all applicable laws and institutional requirements.

Certificate of Analysis (COA)

Choose a report to see its lab results, purity and measured amount. Match the MG amount and lot number to your product.

Ipamorelin

Reinstoff Labs — 5 MGRL-2026-451313 · Lot # US26IPA0502PASSLatestView details ⌄
Laboratory report · Reinstoff Labs

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Certificate of Analysis issued by Reinstoff Labs. Batch ID: US26IPA0502 · HPLC purity: 99.7% · Report code: RL-2026-451313

Reinstoff Labsreinstofflabs.de
REPORT NUMBERRL-2026-451313
SAMPLE

Ipamorelin

CLEARED PEPTIDES · Lot US26IPA0502

PASS
99.7%PURITY BY HPLC
Labeled amount
5.0 mg
Measured amount
5.1 mg
Identity · LC-MS
Confirmed
Analysis completed
Ipamorelin
SterilityNo growth✓ PASS
EndotoxinsWithin specification≤ 5.0 EU/mL✓ PASS
Fentanyl screeningNot detected✓ PASS

Findings relate to the tested sample and recorded method. See the full report.

Issued by Reinstoff Labs. For research use only.

Reinstoff Labs — 5 MGRL-2026-788216 · Lot # US26IPA501PASSView details ⌄
Laboratory report · Reinstoff Labs

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Certificate of Analysis issued by Reinstoff Labs. Batch ID: US26IPA501 · HPLC purity: 99.6% · Report code: RL-2026-788216

Reinstoff Labsreinstofflabs.de
REPORT NUMBERRL-2026-788216
SAMPLE

IPAMORELIN

CLEARED PEPTIDES · Lot US26IPA501

PASS
99.6%PURITY BY HPLC
Labeled amount
5.0 mg
Measured amount
5.1 mg
Identity · LC-MS
Confirmed
Analysis completed
IPAMORELIN
SterilityNo growth✓ PASS
EndotoxinsWithin specification≤ 5.0 EU/mL✓ PASS
Fentanyl screeningNot detected✓ PASS

Findings relate to the tested sample and recorded method. See the full report.

Issued by Reinstoff Labs. For research use only.

Certificate of Analysis — 4.5 MGLot # CDZU8V7May 4, 2026 PASSView details

Certificate summary

Ipamorelin

Certificate of Analysis

View the certificate for the reported test results.

Lot number
CDZU8V7
Labeled amount
4.5 MG

Read the full certificate for test methods, specifications and results.

Certificate preview
View the certificate

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