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Tesamorelin

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Tesamorelin is a research material associated with growth-factor pathway research. Intended for laboratory research and analytical use only; not for human or veterinary use.

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Molecular Structure Explorer

Tesamorelin

Structure of the compound on this page.

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Molecular structure of Tesamorelin

Data from PubChem (NCBI) or a reviewed manual entry, shown only after review. 3D models are computed conformers, not experimental structures. Browsing does not change the product, option or cart. For laboratory research use only.

Product Details

Tesamorelin – Research Grade

Tesamorelin from Cleared Peptides is a research-grade compound supplied for laboratory and analytical investigation. Every lot is third-party tested, and the batch Certificate of Analysis is published before sale. Specifications, CAS number and molecular formula are listed below.

Research use only. Tesamorelin is supplied for laboratory research. It is not a drug, food, cosmetic, or dietary supplement. It is not FDA-approved. It is not for human or veterinary administration. This page does not give a dose or a method of administration. A study cited on this page describes that study’s own test article. It does not make this lot an approved medicine. To check a fact, open the PubMed or DOI link, confirm the authors and year, and match the paper’s compound name, CAS number, or sequence to the specification table. The full method is on the research desk page. Identity and purity for a lot are only what that lot’s certificate of analysis reports. An HPLC percentage is not a sterility result and not an endotoxin result unless the certificate prints those tests.

Tesamorelin Specifications

CompoundTesamorelin
SynonymsTH9507
CAS Number218949-48-5
PubChem CID16137828
Molecular FormulaC221H366N72O67S
Molecular Weight5135.9 g/mol
Sequence / Structure44-residue GHRH analog (N-terminal trans-3-hexenoyl)
FormLyophilized (freeze-dried) powder
Purity≥99% by HPLC (verified per batch – see COA)
StorageStore at −20 °C, sealed, dry and protected from light. Allow vial to reach room temperature before opening.

Tesamorelin in Published Research

Tesamorelin is a synthetic 44-residue analog of growth-hormone-releasing hormone (GHRH) bearing an N-terminal trans-3-hexenoyl group that increases resistance to enzymatic degradation.

It is used as a reference GHRH-receptor agonist in receptor-pharmacology and peptide-stability research.

This summary describes published laboratory research only and makes no claim about effects in humans or animals.

Purity Testing & Certificate of Analysis

Each lot of Tesamorelin is analyzed by an independent laboratory, with identity and purity (or composition, for multi-component preparations) reported on a lot-specific Certificate of Analysis. View current results on our COA page.

Storage & Laboratory Handling

Store at −20 °C, sealed, dry and protected from light. Allow vial to reach room temperature before opening. Minimize freeze–thaw cycles and handle according to your institution’s chemical-hygiene procedures.

Frequently Asked Questions

Is Tesamorelin third-party tested?

Yes. Every lot of Tesamorelin is tested by an independent laboratory for identity and purity, and the batch Certificate of Analysis is published on our COA page.

Can I see the Tesamorelin Certificate of Analysis before ordering?

Yes. Lot-specific COAs are posted on our COA page so you can review analytical data before purchase.

What does Research Use Only (RUO) mean?

RUO products are supplied solely for laboratory and analytical research. They are not medicines, are not for human or veterinary use, and no dosing or administration information is provided.

How should Tesamorelin be stored?

Store at −20 °C, sealed, dry and protected from light. Allow vial to reach room temperature before opening.

Research Guides

Learn more: Ipamorelin research guide · Tesamorelin research guide

Written by the Cleared Peptides Research Desk, the editorial desk of Cleared Wellness Group LLC. This is not a personal profile of a physician or a scientist, and it is not a fictional author. The checking method is public on the research desk page. Last reviewed October 2026.

Tesamorelin research note: a GHRH analogue, and a trial that is not this vial

Research use only. This tesamorelin material is for laboratory research, code TH9507, CAS 218949-48-5. It is not the finished drug used in the NEJM trial, and this note does not repeat that trial’s dose.

The paper, bounded

Falutz, Allas, Blot, and colleagues (New England Journal of Medicine, 2007) randomized adults with HIV and an accumulation of abdominal fat to a growth hormone-releasing factor analogue, tesamorelin, or to placebo, for 26 weeks. The primary endpoint was the change in visceral adipose tissue on computed tomography. IGF-I rose in the tesamorelin arm, which is the endocrine marker expected if a GHRH analogue increased growth-hormone secretion in that study. Lipids moved in the directions the abstract reports. Those sentences describe the trial. They do not describe a lyophilized research lot, and they are not an invitation to reproduce the protocol. PubMed 18057338, DOI 10.1056/NEJMoa072375.

The catalog specification is a 44-residue GHRH analogue with an N-terminal trans-3-hexenoyl group, formula C221H366N72O67S, mass about 5135.9 g/mol. The hexenoyl modification is part of the identity. A 44-residue peptide with a free N-terminus is a different mass. The receptor in this design is the GHRH receptor on pituitary somatotrophs.

Not ipamorelin, and not a blend with MOTS-c

Ipamorelin, in Raun’s 1998 paper, releases growth hormone through a GHRP-like receptor, the pathway later named for ghrelin, and its sequence is a pentapeptide. Tesamorelin is a long GHRH analogue. Both papers are about growth hormone, and they are not the same mechanism. See ipamorelin.

This catalog does not sell MOTS-c mixed with tesamorelin. MOTS-c is a mitochondrial 16-mer. Combining the names does not combine the evidence. That distinction is its own page.

How to verify this note

  1. Open Falutz 2007 and confirm tesamorelin, the HIV population, the CT endpoint, and the IGF-I change. Leave the dose in the paper.
  2. Match CAS 218949-48-5, the 44-residue length, and the trans-3-hexenoyl N-terminus to the certificate.
  3. Do not accept an ipamorelin mass (about 711.9) or a MOTS-c mass (about 2174.6) as confirmation of tesamorelin.

Selected References

Peer-reviewed literature on Tesamorelin, listed as scientific background for laboratory researchers. Citation does not imply endorsement by the authors or any use other than in-vitro research.

  1. Memdouh S, et al. Advances in the detection of growth hormone releasing hormone synthetic analogs. Drug Test Anal. 2021;13(11-12):1871-1887. PubMed 34665524 · DOI

Related Research Compounds

Research Use Only

For laboratory research use only. This product is not a drug, food, cosmetic or dietary supplement, is not FDA-approved, and is not intended for human or veterinary use or for the diagnosis, treatment, cure, mitigation or prevention of any disease. No dosing, administration or therapeutic information is provided. Sold only to qualified researchers; the purchaser is responsible for safe handling and compliance with all applicable laws and institutional requirements.

Certificate of Analysis (COA)

Choose a report to see its lab results, purity and measured amount. Match the MG amount and lot number to your product.

Tesamorelin

Reinstoff Labs — 5 MGRL-2026-606271 · Lot # US26TES501PASSLatestView details ⌄
Laboratory report · Reinstoff Labs

Tap this certificate to view the full certificate.

Certificate of Analysis issued by Reinstoff Labs. Batch ID: US26TES501 · HPLC purity: 99.4% · Report code: RL-2026-606271

Reinstoff Labsreinstofflabs.de
REPORT NUMBERRL-2026-606271
SAMPLE

TESAMORELIN

CLEARED PEPTIDES · Lot US26TES501

PASS
99.4%PURITY BY HPLC
Labeled amount
5.0 mg
Measured amount
5.1 mg
Identity · LC-MS
Confirmed
Analysis completed
TESAMORELIN
SterilityNo growth✓ PASS
EndotoxinsWithin specification≤ 5.0 EU/mL✓ PASS
Fentanyl screeningNot detected✓ PASS

Findings relate to the tested sample and recorded method. See the full report.

Issued by Reinstoff Labs. For research use only.

Reinstoff Labs — 10 MGRL-2026-829543 · Lot # US26TSA1002PASSView details ⌄
Laboratory report · Reinstoff Labs

Tap this certificate to view the full certificate.

Certificate of Analysis issued by Reinstoff Labs. Batch ID: US26TSA1002 · HPLC purity: 99.7% · Report code: RL-2026-829543

Reinstoff Labsreinstofflabs.de
REPORT NUMBERRL-2026-829543
SAMPLE

Tesamorelin

CLEARED PEPTIDES · Lot US26TSA1002

PASS
99.7%PURITY BY HPLC
Labeled amount
10.0 mg
Measured amount
10.2 mg
Identity · LC-MS
Confirmed
Analysis completed
Tesamorelin
SterilityNo growth✓ PASS
EndotoxinsWithin specification≤ 5.0 EU/mL✓ PASS
Fentanyl screeningNot detected✓ PASS

Findings relate to the tested sample and recorded method. See the full report.

Issued by Reinstoff Labs. For research use only.

Certificate of Analysis — 5 MGLot # QGQ35N5March 10, 2026 PASSView details

BTLabs

Tesamorelin · QGQ35N5

PASS
99.7%Purity by HPLC
Lot number
QGQ35N5
Tested
March 10, 2026
Labeled amount
5 MG
Measured amount
5 MG

Read the full certificate for test methods, specifications and results.

Certificate preview
View the certificate