Matrixyl (Palmitoyl Pentapeptide-4)
$149.00 Original price was: $149.00.$108.00Current price is: $108.00.
Matrixyl is a research material associated with peptide signaling research. Intended for laboratory research and analytical use only; not for human or veterinary use.
Discount per quantity
| Quantity | 2 | 3 | 4 | 5 | 10 - 15 |
|---|---|---|---|---|---|
| Price | $97.20 | $91.80 | $86.40 | $81.00 | $75.60 |
Molecular Structure Explorer
Matrixyl
Structure of the compound on this page.

Product Details
Matrixyl (Palmitoyl Pentapeptide-4) – Research Grade
Matrixyl (Palmitoyl Pentapeptide-4) from Cleared Peptides is a research-grade compound supplied for laboratory and analytical investigation. Every lot is third-party tested, and the batch Certificate of Analysis is published before sale. Specifications, CAS number and molecular formula are listed below.
Research use only. Matrixyl (Palmitoyl Pentapeptide-4) is supplied for laboratory research. It is not a drug, food, cosmetic, or dietary supplement. It is not FDA-approved. It is not for human or veterinary administration. This page does not give a dose or a method of administration. A study cited on this page describes that study’s own test article. It does not make this lot an approved medicine. To check a fact, open the PubMed or DOI link, confirm the authors and year, and match the paper’s compound name, CAS number, or sequence to the specification table. The full method is on the research desk page. Identity and purity for a lot are only what that lot’s certificate of analysis reports. An HPLC percentage is not a sterility result and not an endotoxin result unless the certificate prints those tests.
Matrixyl Specifications
| Compound | Matrixyl (Palmitoyl Pentapeptide-4) |
|---|---|
| Synonyms | Pal-KTTKS |
| CAS Number | 214047-00-4 |
| PubChem CID | 9897237 |
| Molecular Formula | C39H75N7O10 |
| Molecular Weight | 802.1 g/mol |
| Sequence / Structure | Palmitoyl-Lys-Thr-Thr-Lys-Ser |
| Form | Lyophilized (freeze-dried) powder |
| Purity | ≥99% by HPLC (verified per batch – see COA) |
| Storage | Store at −20 °C, sealed, dry and protected from light. Allow vial to reach room temperature before opening. |
Matrixyl in Published Research
Matrixyl is the trade name for palmitoyl pentapeptide-4 (Pal-KTTKS), a lipidated fragment of the type I procollagen propeptide. The palmitoyl group increases lipophilicity relative to the free KTTKS pentapeptide.
It is a standard reference peptide in cosmetic-science research, studied in fibroblast cultures for extracellular-matrix protein expression.
This summary describes published laboratory research only and makes no claim about effects in humans or animals.
Purity Testing & Certificate of Analysis
Each lot of Matrixyl is analyzed by an independent laboratory, with identity and purity (or composition, for multi-component preparations) reported on a lot-specific Certificate of Analysis. View current results on our COA page.
Storage & Laboratory Handling
Store at −20 °C, sealed, dry and protected from light. Allow vial to reach room temperature before opening. Minimize freeze–thaw cycles and handle according to your institution’s chemical-hygiene procedures.
Frequently Asked Questions
Is Matrixyl third-party tested?
Yes. Every lot of Matrixyl is tested by an independent laboratory for identity and purity, and the batch Certificate of Analysis is published on our COA page.
Can I see the Matrixyl Certificate of Analysis before ordering?
Yes. Lot-specific COAs are posted on our COA page so you can review analytical data before purchase.
What does Research Use Only (RUO) mean?
RUO products are supplied solely for laboratory and analytical research. They are not medicines, are not for human or veterinary use, and no dosing or administration information is provided.
How should Matrixyl be stored?
Store at −20 °C, sealed, dry and protected from light. Allow vial to reach room temperature before opening.
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Research Guides
Learn more: Matrixyl research guide
Selected References
Peer-reviewed literature on Matrixyl (Pal-KTTKS), listed as scientific background for laboratory researchers. Citation does not imply endorsement by the authors or any use other than in-vitro research.
- Palladino P, et al. Conformation and self-association of peptide amphiphiles based on the KTTKS collagen sequence. Langmuir. 2012;28(33):12209-15. PubMed 22834769 · DOI
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Research Use Only
For laboratory research use only. This product is not a drug, food, cosmetic or dietary supplement, is not FDA-approved, and is not intended for human or veterinary use or for the diagnosis, treatment, cure, mitigation or prevention of any disease. No dosing, administration or therapeutic information is provided. Sold only to qualified researchers; the purchaser is responsible for safe handling and compliance with all applicable laws and institutional requirements.
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