Molecular Structure Explorer
LC216 Blend
Structure of the compound covered in this guide.
Verified structure pending review
Last reviewed: October 2026 · Cleared Peptides research team
Research use only. LC216 Blend: Components and Biochemical Notes is supplied for laboratory research. It is not a drug, food, cosmetic, or dietary supplement. It is not FDA-approved. It is not for human or veterinary administration. This page does not give a dose or a method of administration. A study cited on this page describes that study’s own test article. It does not make this lot an approved medicine. To check a fact, open the PubMed or DOI link, confirm the authors and year, and match the paper’s compound name, CAS number, or sequence to the specification table. The full method is on the research desk page. Identity and purity for a lot are only what that lot’s certificate of analysis reports. An HPLC percentage is not a sterility result and not an endotoxin result unless the certificate prints those tests.
LC216 is an aqueous research blend. This page names the components and a published biochemical pathway for each one.
Component names match the product record. A CAS number is included only when the named chemical form has a public registry entry. Pathway notes describe published biochemistry. They are not statements of benefit or use.
Components
| Component | CAS number | Published biochemical note |
|---|---|---|
| L-Carnitine | 541-15-1 | Described as a carrier in the transfer of long-chain fatty acyl groups across the inner mitochondrial membrane, in the β-oxidation pathway. |
| L-Arginine | 74-79-3 | A substrate of nitric oxide synthase and an intermediate of the urea cycle in published enzyme pathways. |
| Methionine | 63-68-3 | A sulfur amino acid that is a methyl source in the S-adenosylmethionine transmethylation pathway. |
| Inositol | 87-89-8 (myo-inositol) | A cyclitol in phosphatidylinositol membrane-lipid pathways. |
| Choline | Salt form is lot-specific. CAS is not stated here. | A precursor of phosphatidylcholine in published phospholipid pathways, and a participant in one-carbon metabolism. |
| Pyridoxine (B6) | 65-23-6 for pyridoxine. The hydrochloride salt is a different CAS. | Converted in enzyme pathways to pyridoxal 5′-phosphate, a cofactor for amino-acid transamination and decarboxylation. |
| Dexpanthenol (B5) | 81-13-0 | A pantothenic-acid precursor that is incorporated into coenzyme A in published cofactor pathways. |
| Methylcobalamin (B12) | 13422-55-4 | A cobalamin cofactor of methionine synthase in the published methylation cycle. |
Solubility of the finished aqueous blend is a property of that formulation and is not given a single public figure here. See the lot COA.
LC216 blend · L-Carnitine guide · COA page
Other names
LC216 is the Cleared Peptides catalog name for this aqueous blend. It is not one peptide. Carnitine, arginine, methionine, inositol, choline, pyridoxine, dexpanthenol, and methylcobalamin are separate chemicals.
Published pathways for the components
The notes below describe published enzyme pathways for the named chemicals. They are not studies of this blend as one substance, and they are not statements of benefit or use.
L-Carnitine (CAS 541-15-1) is described as the carrier for long-chain fatty acyl groups across the inner mitochondrial membrane. L-Arginine (CAS 74-79-3) is a nitric oxide synthase substrate and a urea-cycle intermediate. Methionine (CAS 63-68-3) is a methyl source for S-adenosylmethionine. Methylcobalamin (CAS 13422-55-4) is a cobalamin cofactor of methionine synthase in that same published methylation cycle. Pyridoxine (CAS 65-23-6) is converted toward pyridoxal 5′-phosphate, the cofactor used by amino-acid transaminases; the hydrochloride salt is a different CAS number.
Dexpanthenol (CAS 81-13-0) is a pantothenic-acid precursor that published routes incorporate into coenzyme A. Myo-inositol (CAS 87-89-8) is the cyclitol in phosphatidylinositol. Choline’s salt is lot-specific and is left unnamed as a CAS number here. See the L-carnitine guide and the SHB blend guide for the arginine and carnitine rows those pages share.
Analytical testing notes for LC216 Blend
LC216 Blend is identified in this guide. An identity test compares a measurement with those values. A mass spectrum is the usual measurement for a peptide. FTIR, when a certificate uses it, is a supporting infrared fingerprint and is less specific for closely related sequences.
This page compares more than one component. A single purity percentage is ambiguous unless the certificate says whether each component was resolved, identified, and quantified. Identity and content should be traceable to each named material. A chromatogram with several intentional peaks is expected; those peaks are not automatically impurities.
HPLC purity for this material is an area-percent result at the wavelength and gradient the laboratory states, commonly ultraviolet detection near 214 nm on a reversed-phase column. The instrument is a gradient pump, injector, column oven, and UV or diode-array detector. That percentage is not the number of milligrams in the vial. Water, acetate, trifluoroacetate, and other UV-silent material can dominate the gross weight while the purity figure stays high. Net peptide content, from an assay or amino-acid analysis, is the separate result to read when the certificate reports it.
A sterility test and an endotoxin test are not included in a chemical purity result. The compendial sterility test is a culture method (USP <71>): membrane filtration or direct inoculation into fluid thioglycollate medium and soybean-casein digest medium, incubated for 14 days. A PCR sterility screen uses a thermal cycler to detect microbial DNA and is a different method. The endotoxin test (USP <85> LAL, or USP <86> recombinant Factor C) reports endotoxin units with an incubating reader or a cartridge reader. Use a result only when that method is printed on the lot certificate. One published example in this catalog states that the report does not cover microbial contamination or endotoxins. The full description of equipment, standards, and how US laboratory accreditation works is in peptide analytical testing. Lot records are on the COA page.
Frequently Asked Questions
Is LC216 one compound?
No. LC216 is a catalog code for a blend. Use the component CAS numbers, not a single number for the bottle.
How is LC216 different from SHB?
Both are multi-component research blends. LC216’s table includes methionine, methylcobalamin, pyridoxine, and dexpanthenol. SHB’s table includes ornithine, citrulline, lysine, glutamine, proline, taurine, and N-acetylcysteine. Compare the component tables rather than the catalog codes.
Is LC216 for human use?
No. It is supplied for laboratory research use only and is not for human or veterinary use.
Selected References
Peer-reviewed literature listed as scientific background for laboratory researchers. Citation does not imply endorsement by the authors, and it is not a statement of benefit or use. These papers do not study the finished blend as a single substance.
- Förstermann U, Sessa WC. Nitric oxide synthases: regulation and function. Eur Heart J. 2012;33(7):829-837. Cited here only for the enzyme fact that nitric oxide synthase uses L-arginine as a substrate and requires NADPH, FAD and FMN as cofactors. PubMed 21890489 · DOI
- Bremer J. Carnitine—metabolism and functions. Physiol Rev. 1983;63(4):1420-1480. Cited here for carnitine as a carrier of long-chain acyl groups across the inner mitochondrial membrane, and for methylation of lysine in the published carnitine biosynthesis route. PubMed 6361812
Research Use Only Notice
This guide is provided for educational and laboratory reference purposes. It summarizes published structural and biochemical literature. It does not describe, recommend, or imply any use in humans or animals. Products sold by Cleared Peptides are for laboratory research use only. They are not drugs, foods, cosmetics, or dietary supplements, are not FDA-approved, and are not intended to diagnose, treat, cure, mitigate, or prevent any disease. No dosing, administration, or use instructions are provided.
